Preclinical Cancer Imaging
نویسنده
چکیده
• Chemical Exchange Saturation Transfer (CEST) based Magnetic Resonance Imaging (MRI) methods inherently have superior sensitivity to molecular changes in tumors. • CEST MRI provides unconventional and in many cases molecular specific image contrast. CEST contrast can be turned on and off. • CEST MRI is sensitive to pH and molecular changes in tumors. • It enables the differential diagnosis between radiation necrosis and tumor recurrence. • It enables high resolution imaging of glucose metabolism and protease activity in cancer. • It has the potential to serve as an imaging biomarker for diagnosis of tumors and monitoring tumor response to therapy.
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تاریخ انتشار 2013